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Anabolic-androgenic steroids abuse : ウィキペディア英語版
Anabolic-androgenic steroids abuse
Research data indicates that steroids affect the serotonin and dopamine neurotransmitter systems of the brain.〔(Dopinglinkki > Anabolic steroids induce long-term changes in the brain )〕 In an animal study, male rats developed a conditioned place preference to testosterone injections into the nucleus accumbens, an effect blocked by dopamine antagonists, which suggests that androgen reinforcement is mediated by the brain. Moreover, testosterone appears to act through the mesolimbic dopamine system, a common substrate for drugs of abuse. Nonetheless, androgen reinforcement is not comparable to that of cocaine, nicotine, or heroin. Instead, testosterone resembles other mild reinforcers, such as caffeine, or benzodiazepines. The potential for androgen addiction remains to be determined.
Anabolic steroids are not psychoactive and cannot be detected by stimuli devices like a pupilometer which makes them hard to spot as a source of neuropsychological imbalaces in some AAS users.
==Abuse potential==
The Diagnostic Statistical Manual IV (DSM IV) and the International Classification of Diseases, Volume 10 (ICD 10) differ in the way they regard Anabolic-Androgenic Steroids' (AAS) potential for producing dependence.
DSM IV regards AAS as potentially dependence producing. ICD 10 however regards them as non-dependence producing. Anabolic steroids are not physically addictive but users can develop a psychological dependence on the physical result.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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